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Contrastingly, no statistically significant signal values were observed in other age groups, including younger adults, adults, and the elderly, based on both ROR and EBGM05

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Whether this elevation in females is a consequence of the decreased alcohol intake or depends on neurobiological underpinnings remains unknown.15, 16, 17 It is worth considering the potential involvement of vasopressin in the observed increase in water intake since GLP-1R signalling inhibits the production of this hormone

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In vitro, in differentiated human DA neurons, IR was associated with increased -synuclein and ROS levels, as well as mitochondrial depolarization, which may be mediated by polo-like kinase-2