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We therefore cannot rule out that exercise may have influenced the results seen here, and activity meters should be used in future studies

Other medications usually continue as is

Common short-term effects include: Nausea after meals Vomiting, especially after large or oily meals Loose stools or diarrhoea Constipation Abdominal discomfort Reduced hunger Early fullness Mild headache Tiredness Dizziness Low blood sugar, mainly in people with diabetes who also take insulin or sulfonylurea medicines Dehydration if vomiting or diarrhoea is frequent Food aversions or dislike for certain smells Mild symptoms can often be managed with diet changes and hydration

A crucial note of caution: ondansetron should generally be used only for short periods to quell acute nausea and not as a long-term crutch to allow for rapid dose increases

Approved GLP-1 RAs in Canada include semaglutide, liraglutide, and dulaglutide

Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole-kindled mice