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A 2025 JAMA Internal Medicine trial compared oral versus extended-release injectable naltrexone in 248 hospitalized patients with alcohol use disorder
If a patients body is already producing GLP-1 at normal or elevated levels, prescribing a long-acting agonist isnt correcting a deficit

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5F), suggesting that intracellular Ca 2+ is indeed associated with the exendin-4 effect

+ For trips over 24 hours, yes particularly in summer or in warm climates
