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The headline finding On average, people regain 0.4 kg per month after stopping WMMs

Recent data and clinical updates provide a glimpse into manufacturer approaches: Efficacy: Efficacy: Currently approved incretin mimetics are viewed as highly efficacious across diabetes and obesity

32,33 Under physiological conditions, besides the paracrine secretion pathway in the gastrointestinal tract, most endogenous GLP-1 in circulation is locally deactivated by DPP-4 and the liver, 34 making it difficult to directly enter the CNS through the blood-brain barrier