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While SGLT2-i and GLP-1RA may offer additive or synergistic benefits in reducing BP and cardiovascular risk, current guidelines do not support their role as first-line antihypertensive agents or early adjunctive therapies over established agents such as thiazide diuretics, renin-angiotensin system (RAS) inhibitors, or calcium channel blockers (CCBs)

Our findings can better inform the future design of vaccine development against norovirus. Norovirus spreads easily through contaminated food, water and surfaces, often causing outbreaks in schools, cruise ships and health care facilities

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These differences may have implications for the sustainability of weight loss and warrant further investigation in long-term studies, particularly as it relates to potential effects on the central nervous system (7173)

BBB, blood brain barrier

This approach isnt designed for people with diabetes, who are more likely to need medication for the long term