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Semaglutide 24 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial

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The tolerance and adaptation hypothesis GLP-1 receptor agonists work by mimicking hormones your body already produces

When in doubt, do not use the medication

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The GLP-1 component helps slow down gastric emptying, which means food stays in your stomach longer