glp-1 and chronic kidney disease Receptor Agonists Diabetic Disease: A Call of Attention to Nephrologists SGLT2 vs GLP-1 for CKD:

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Clinical Epidemiology

Skibicka KP

[23] Something interesting to note about this study is the lack of dose response in the findings

Extensive clinical trials have shown that GLP-1 receptor agonists can lead to significant, sustained weight loss in people with obesity or overweight, even if they do not have diabetes

By activating GLP-1Rs on glial cells, these agents suppress pro-inflammatory cytokines (IL-1, TNF-) and block NF-B-mediated inflammatory cascades [10,24]