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Transl Psychiatry 6 , e809 (2016)
DPP-4 Inhibition Has Beneficial Effects on the Heart after Myocardial Infarction
Who could wait for approval and availability: patients with needle anxiety and stable health
Similarly, the STEP-6 study 25 reported a 3% incidence of psychiatric events with semaglutide 2.4 mg, compared to 1% in the placebo group
S.et al (2016)
The mechanism is straightforward: GLP-1 RAs enhance glucose-dependent insulin secretion, and stacking that on top of glucose-independent insulin release from exogenous insulin or sulfonylureas removes the glucose-dependent safety brake
