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In contrast, in intestinal cells and certain brain regions, prohormone convertase 1/3 (PC1/3) processes proglucagon to generate GLP-1, intervening peptide-2 (IP-2), and GLP-2

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Semaglutide: A GLP-1 Receptor Agonist Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist , which means it mimics a natural hormone that helps regulate blood sugar and appetite