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Moreover, adiponectin has been shown to upregulate Bcl-2-associated X protein (Bax), a pro-apoptotic protein, while downregulating B-cell lymphoma 2 (Bcl-2), an anti-apoptotic protein, leading to increased apoptosis in cancer cells [18]

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[email protected] (C.D.) Received Date: November 21, 2024 Accepted Date: January 06, 2025 Published Online: January 15, 2025 REFERENCES ABOUT THIS ARTICLE Cite this article: Zhou L., He S., Li C., et al

34 These studies suggest that the impact of lifestyle interventions on breast cancer recurrence may be mediated by effective weight loss and adherence, and importantly, even modest weight change can be associated with meaningful clinical benefit