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Comparative effectiveness of GLP-1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta-analysis was published in The BMJ in January 2024

[12] [13] Red flags that require urgent medical attention include unexplained weight loss, fever, focal neurological deficits, or inflammatory joint swelling, as these may indicate alternative diagnoses requiring different management

In the interim, continued shared decision making with patients and clinical vigilance for pancreatic diseases in patients on GLP-1RA therapy remains prudent

Both formulations are manufactured by Eli Lilly and can be obtained through: Primary care physicians Endocrinologists Weight management specialists Telehealth weight loss clinics Compounding pharmacies (compounded tirzepatide versions) Insurance coverage varies widely

Jin T, Weng J