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Beyond objective clinical outcomes, GI motility disturbances can substantially affect patient-reported outcomes, including daily functioning, dietary intake, and overall quality of life
Starting at a low dose of 0.25 mg in the first week is a crucial step to minimize potential gastrointestinal side effects that many patients experience when beginning treatment with semaglutide GLP-1

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The amount of endogenous corticosteroids created by the HPA-axis is equivalent to 7.5mg of prednisolone daily (or about 8mg of prednisone daily)
Nielsen M, Andreatta M

This is where dietary supplements have come into play
