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Weight reduction can improve IR, muscle energy balance, and muscle microcirculation by restoring glucose metabolism and oxidative phosphorylation and improving mitochondrial function

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[DOI] [PubMed] [Google Scholar] 112.Blher M, Aras M, Aronne LJ, et al

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Clinical Contraindications Not appropriate for patients with a personal or family history of medullary thyroid carcinoma or MEN 2, or for patients who are pregnant or breastfeeding
