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Negative Mental Health Impact: Gastrointestinal Side Effects: Some people taking semaglutide may experience gastrointestinal side effects such as nausea, vomiting, diarrhea, or abdominal pain

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It appears that only in RYGB and SG patients intestinal derived GLP-1 has a true endocrine role, while in healthy individuals, localized, paracrine and neuronal signals primarily define the GLP-1 physiology

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The common hepatic branch of the vagus is not required to mediate the glycemic and food intake suppressive effects of glucagon-like-peptide-1

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Some plaintiffs who have filed lawsuits allege that Eli Lilly should have warned them about Mounjaro and a possible association with vision loss caused by NAION

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The shedding, while distressing, was not severe enough to outweigh the metabolic benefits of continued treatment

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For now, the available data supports both approaches

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