.6 semaglutide Post hoc analysis of SUSTAIN 6 and PIONEER 6 trials suggests that people with type 2 diabetes at high cardiovascular risk treated with experience more stable kidney function compared with placebo Cardiovascular risk reduction with once-weekly

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Researchers have also reported cardiovascular benefits, with several studies showing reductions in heart attack and stroke risk among individuals using GLP-1 therapies

Frequent heartburn can be a symptoms of gastroesophageal reflux disease (GERD), a side effect that was reported in the drugs clinical trials

Doctors suggest taking 2.4 mg as the maintenance dose when well-tolerated by patients, and 1.7 mg as the maintenance dose when the patient cannot tolerate the side effects of a higher dose

Endocrinology 166:bqaf028 Kaur M, Misra S (2024) A review of an investigational drug retatrutide, a novel triple agonist agent for the treatment of obesity