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injected low-dose liraglutide and exendin-4 were also attenuated by subdiaphragmatic vagal deafferentation [687,691], but longer-term effects of these compounds on food intake did not depend on intact vagal afferents [691]

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Of note, glomerular hyperfiltration could be exacerbated by other hormonal changes associated with scarce glucose control, such as high glucagon levels [49, 51]

SCFAs can affect the integrity of the intestinal mucosa, glucose and lipid metabolism, immune system, and inflammatory responses