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78 Recent data also show the potential efficacy of GLP-1RAs in renal function in patients without T2D

GLP-1 RAs showed significant reductions in all anthropometric parameters, while SGLT2is was observed to improve WHR and AGF ratio (in addition to reduced body weight observed with SGLT2is/metformin combination)

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These findings indicate a shift toward lower inflammatory signaling and improved vascularimmune regulation