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"These incidents can occur after the first dose of these sleep medicines or after a longer period of treatment, and can occur in patients without any history of these behaviors and even at the lowest recommended doses," according to FDA Acting Commissioner Ned Sharpless, M.D.

But in his view, GLP-1s are the accelerant and yet it's the one were still ranking fifth or sixth when we talk about headwinds

Studies addressing skeletal muscle quantity, quality, and functional capacity are needed to clarify the effects of GLP-1 RAs on sarcopenic obesity in older adults.