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Tirzepatide can aid in weight loss by reducing appetite and improving metabolic functions

The titration starts at 0.8 mg and increases over several months through up to six dose levels, with a maximum maintenance dose of 17.2 mg

The primary elimination pathway involves proteolytic degradation rather than renal excretion, which explains this renal-independent clearance

Instead, metabolism is regulated by a network of hormones working together

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