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IntroductionGlucagon-like peptide-1 receptor agonists (GLP-1 RA) are novel agents with proven cardiovascular (CV) benefits

Researchers are working to understand the effects of these popular new therapies on ocular structures.

However, sudden visual loss, a new blind area or rapidly worsening eyesight requires emergency evaluation

Studies and meta-analyses have revealed that postprandial GLP-1 levels increase after the Roux-en-Y gastric bypass and sleeve gastrectomy, but fasting GLP-1 levels do not increase significantly

Key milestones highlighted in this timeline: 1999 Orlistat (Xenical) The first long-term FDA-approved anti-obesity medication of the modern era

It is not approved yet, but the data is starting to demand attention