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Id also raise the question of whether the incretins and other GLP-1 agonists will ever be free of adverse GI symptoms, as it seems intrinsic to the drugs mechanism.

other outcomes were cardiovascular and total death, nonfatal myocardial infarction (MI), nonfatal stroke, hospitalization for heart failure (HHF), and renal outcome

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After a few years of injectable dominance, oral formulations are emerging as a game-changer for adherence and ease of use thanks to their lack of cold-chain requirement, but also a game-changer for their ability to unlock the long-term maintenance opportunity [14]

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