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This evidence supports the model that GLP-1 medications work best as ongoing therapies rather than short-term interventions

Emerging medications like retatrutide may eventually surpass all current options, and the precise dosing comparisons between medications help clinicians optimize individual treatment plans

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The math favors those with more to lose, which is also clinically appropriate

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J Clin Endocrinol Metab 100(6):22482253