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Morris began by outlining the biological rationale for targeting prostate-specific membrane antigen (PSMA), a highly expressed and therapeutically actionable surface protein in advanced prostate cancer

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For patients with severe GI side effects, starting with microdosing and increasing slowly can improve tolerability and prevent therapeutic disruption
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Avoid certain foods: Limit high-protein foods (chicken, fish, eggs), whole legumes and grains, and dairy (cheese, whole milk)
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