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Bastick, A
Incapsula incident ID: 461000720060350835-241290932007014928

Lim WH, Lok CE, Kim SJ, Knoll G, Shah BR, Naylor K, Luo B, Vinegar M, Dixon SN, Hawley C et al

[20] Cytochrome isoforms affected by grapefruit components include CYP1A2, CYP2C9, and CYP2D6, [21] [22] [23] [24] [25] but CYP3A4 is the major CYP enzyme in the intestine

The future may hold medicines that prevent chronic diseases before they start, aiming for longer, healthier lives rather than just treating illness when it appears

Seven drugs have currently been approved for the treatment of Type 2 diabetes mellitus, including short-acting agents like exenatide and lixisenatide, as well as long-acting injectable agents such as albiglutide, dulaglutide, liraglutide, and semaglutide. GLP-1s regulate lipid metabolism, reducing the effects of hyperlipidemia and helping to lower the risk for both chronic kidney disease (CKD) and diabetic kidney disease. They have also been shown to reduce oxidative stress, which includes stimulating glomerular filtration and reducing vasoconstriction, slowing the progression of CKD. Limited data from clinical trials have been published on the effects of GLP-1 receptor agonists in individuals with post-liver transplant diabetes mellitus (PTDM)
