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Comparative Pharmacology: Benchmark efficacy against dual agonists like Tirzepatide to quantify the added benefit of glucagon receptor activation on metabolic rate and fat oxidation

Additionally, potential GLP-1RA side effects were assessed for comprehensive safety evaluation

this peptide resulted in weight loss and had lipid-lowering and glucose-lowering effects in mice with diet-induced obesity, which were superior to the effects seen with a GLP-1 receptor-selective agonist [77]

[DOI] [PubMed] [Google Scholar] 73.Cai Y., Hu X., Yi B., Zhang T., Wen Z

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Ahmad E, Lim S, Lamptey R, Webb DR, Davies MJ
