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Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-alpha in mice
Already approved for prescription in Europe, USA, Canada, Australia, Japan and Switzerland, orally administered semaglutide has been shown to be effective, safe and well tolerated
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Shigeto M, Ramracheya R, Tarasov AI et al (2015) GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
He is a division chair of supply chain management at Mayo Clinic
