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503b: the difference that matters

Incretin mimetics have established a massive market in diabetes and obesity, and have yet to reach their peak potential in these therapeutic areas

These data suggest that although the cardioprotective actions of GLP-1 in the isolated mouse heart require tmAC, those of GLP-1(2836) depend solely on sAC

Mechanistically, exercise promotes insulin sensitivity, enhances blood circulation, and improves glucose uptake via insulin-dependent and independent pathways, such as GLUT-4 translocation

Together with inward movement of -helical extended TM2, raised ECL1 of GLP-2R forms extensive interaction with the C-terminal half of GLP-2 (Fig

MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine