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Svegliati-Baroni G, Ridolfi F, Di Sario A, Casini A, Marucci L, Gaggiotti G, Orlandoni P, Macarri G, Perego L, Benedetti A, Folli F

The authors suggest that serum IGF-1 facilitates brain A removal by enhancing the transport of A carrier proteins (e.g., transthyroxine, apolipoprotein J, and albumin) across the BBB, thereby improving choroid plexus barrier transport and increasing A efflux from the brain, thereby regulating brain A clearance [183, 185]

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