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Also at higher doses, it acts on centers in the brain and suppresses appetite

Finally, summarizing the data on metabolic outcomes is challenging because of significant variability in effects

Primary outcome was weight loss post at least 3 months of therapy

10 Declining ovarian function during menopause is associated with increased proinflammatory cytokines that have been linked to a higher risk of depression and mood disorders, including interleukin-6 (IL-6), and tumor necrosis factor- (TNF-)