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R., Zarezadeh R., Latifi Z., Laleh S

Increase in oxidative stress due to long-term hyperglycemia is believed to augment proinflammatory protein levels, angiotensin II, protein kinase C activation, and transforming growth factor-beta (TGF-) expression

Identifying and managing these triggers can be instrumental in preventing future outbreaks

33 , 38 , 39 , 40 , 41 , 42 , 43 , 44 GIP also enhances glucosestimulated insulin secretion in people without type 2 diabetes whereas this effect is diminished in people with type 2 diabetes, but unlike GLP1, it stimulates glucagon secretion in hypoglycaemic states

You eat less because of reduced appetite

Your GP may consider prescribing anti-emetic medications for short-term use during the adjustment period if lifestyle measures prove insufficient