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Second, the multidifferentiation potential of MSCs should be tightly controlled, and inducing the differentiation of MSCs into dopaminergic neurons before transplantation for PD treatment may be necessary to improve their therapeutic effects

Moreover, LPS treatment upregulated nuclear NF-b p65 (pS536) protein levels, while exendin-4 reduced nuclear NF-B p65 (pS536) levels, suggesting that GLP-1 analogs may modulate inflammatory cytokine expression by interfering with NF-B p65 phosphorylation and translocation to the nucleus (Figure 7)

Use bacteriostatic water (0.9% benzyl alcohol) for multi-dose vials