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Complicaciones de retinopata diabtica: Particularmente con semaglutida, se ha observado un empeoramiento temporal de la retinopata diabtica en algunos pacientes, especialmente con reduccin rpida de glucosa

The SURMOUNT clinical program demonstrated substantial weight reductions establishing tirzepatide as one of the most effective obesity medications available

In these trials, participants achieved a mean weight loss of approximately 15% of body weight over 68 weeks-correlating with a substantial calorie deficit that contributes to initial fatigue

Pharmacol Rev 77:100002

doi: 10.1007/s00125-020-05158-9

The growth hormone pathway that tesamorelin activates supports the very tissues that aggressive weight loss strategies tend to sacrifice