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Greater knowledge of the mechanisms of fat fuel partitioning that underlie the metabolic and behavioral actions of GLP-1RAs could also provide a roadmap for the development of new or adjunctive pharmacological or other strategies for treating obesity and associated metabolic diseases," they conclude

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MMSc and colleagues showed that combining ixekizumab with tirzepatide led to greater disease control than ixekizumab alone in adults with psoriatic arthritis and overweight or obesity

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This suggests that these cells are not just passive targets, but key mediators of hepatic improvement