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10.1056/NEJMoa2206038 [DOI] [PubMed] [Google Scholar] 44.Research C for DE and FDA

Fructans are a type of carbohydrate that can cause digestive discomfort for individuals with FODMAP sensitivities

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However, they aren't without adverse reactions, and they carry rare, but significant, risks

PubMed CrossRef Marso SP, Daniels GH, Brown-Frandsen K, et al

From baseline to week 68, the mean change in knee pain, assessed using the WOMAC pain score, was a reduction of 41.7 points for semaglutide and a decrease of 27.5 points for placebo, with an estimated treatment difference of 14.1 points, which was statistically significant [167]
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