astria therapeutics glp-1 receptor agonist weight management diabetes treatments for vs GLP-1 for Loss: What's Changing for Patients and Pharmacies? Targeting GLP-1, GIP & GCG

GLP-1 medications mimic the action of the GLP-1 hormone that is naturally released by the body and can help to reduce appetite, decrease overeating, and lose weight

(N Y) 2 (11), 12031230

Historically, this increased insulin response mediated by GLP-1 and GIP had been attributed to factors termed incretins (derived from incretion, a term used at that time to refer to a secretion that remains inside the body), hence the name incretin effect is still used today to describe the rise in insulin mediated by the action of these hormones

However, there is uncertainty around their effects when used in pregnancy

DPP-4 inhibitors double the circulating concentrations of both GLP-1 and GIP

P., Melguizo, M