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GLP-1 RAs (short for glucagon-like peptide-1 receptor agonists) are medicines originally developed to treat type 2 diabetes

But alongside their rapid adoption, troubling patterns have emerged: serious gastrointestinal complications, gallbladder disease, and cases of gastroparesis that leave patients in chronic pain or require emergency surgery

The trade-off is cost, though the gap between compounded and brand-name pricing has narrowed significantly

Patrick Blatchford, MD, FACS brings you the latest advancements in weight loss

The most common issues are nausea, vomiting, diarrhea, and constipation

But everything changed in 1921