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Once again, the design strategy was contrary to the mainstream view in that GIPR agonism was thought to add little to glycemic lowering in people with diabetes, and could prove deleterious for weight gain

Glucose control The SURPASS studies enrolled populations that were similar in terms of baseline HbA1c levels, which ranged from 7.9 to 8.5% [2, 3, 59,60,61] and found a statistically significant reduction in HbA1c already at the 5 mg dose, demonstrating a greater efficacy of tirzepatide compared to placebo or active comparator [2, 3, 59,60,61]

Ogorek CP, Davidson L, Fisher RS et al

Clients are promised that they will lose 10% of their body weight within the first year and that they will shed the pounds without any restrictive diet or intense exercise. According to the Journal, NextMed has capitalized on the surging popularity of Ozempic and other drugs

SOURCE: JAMA Pediatrics , Oct

While this has been done in research settings, it is not practical for routine clinical therapy
