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Anti-obesity drugs should be offered as initial treatment of overweight and obesity for adults with weight-related comorbidities and for those at high risk of complications, and as a component of first-line treatment for patients with obesity and overweight without comorbidities

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In such cases, new GLP-1 receptor agonist (RA) weight loss medications might be beneficial because weight regain or inadequate weight loss limits the health benefits of surgery.Previously, if people started regaining weight after surgery, they might try to modify their diet and exercise, and in some cases, they might even qualify for a revisional surgery

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This review systematically summarizes the therapeutic potential ...

Semaglutide was developed for patients with specific weight-related conditions
