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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs) show substantial efficacy in regulating blood glucose levels and lipid metabolism, initially as an effective treatment for diabetes mellitus

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Researchers used an indirect comparison to evaluate their relative efficacy in patients with T2D inadequately controlled on metformin monotherapy, with change in HbA1c and body weight at approximately one year as the primary outcomes

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Higher doses of the drug have been shown to drive more weight loss

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