glp 1 severe constipation GLP-1 Constipation: Miralax vs Metamucil (The Fiber Trap) Managing GLP-1/GIP side effects with
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In AS, inflammation reduces the mucus layer and disrupts tight junctions, desmosomes, and adherens junctions that regulate epithelial permeability [31]
Furthermore, BBR enhances bile acid production, aids in cholesterol excretion, and regulates hepatic cholesterol synthesis by phosphorylating HMG-CoA reductase [49,50]

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People taking GLP-1 medications who experience vomiting, diarrhea, or reduced fluid intake may need additional fluids to stay hydrated
Yet, medications like Wegovy and Ozempic, which could help address these issues, remain priced at over $1,300 per month, putting them out of reach for millions who need them most (CDC, 2024)

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