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The trial was designed to estimate the treatment effects of once-weekly subcutaneous Semaglutide among obese patient with HFpEF
Some may feel effects sooner, while others may need to reach higher doses
This metabolic rebalancing may activate thermoregulatory centers in the hypothalamus, triggering hot flashes or night sweats
This dual mechanism produces a distinctly complementary research profile: GLP1R activation: Reduces appetite, delays gastric emptying, and enhances glucosedependent insulin secretion via central satiety signalling
