how long does nausea from glp 1 last Waking up nauseous at night on your GLP-1? You're not imagining it — and you're not alone. Nighttime on GLP-1 medications is one of the most common reasons people consider stopping Throwing Up on a GLP-1:

Less than 0.2% of liraglutide injection-treated patients discontinued due to injection site reactions

Diabetes itself increases NAION risk, creating particularly dangerous situations when patients take GLP-1 medications that multiply already elevated baseline risk

However, if you experience severe vomiting early in your GLP-1 treatment, use backup contraception for that cycle

In January 2025, researchers from Medication Weight Loss Clinic, Ireland, found that GLP-1 agonists showed positive results in managing co-occurring obesity and reducing alcohol intake

Increase hydration aggressively

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R