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The results of the in vivo study mirrored these findings, aligning with previous research (19-22)

In addition, to help decrease neuroinflammation, a key factor driving PD pathogenesis, GLP-1 RAs modulate immune cell activity and suppress the release of proinflammatory cytokines, such as TNF-, IL-6, and IL-1, all of which play a major role in neuroinflammation

2.2 The role of GLP-1 in innate-like T lymphocytes Invariant Natural Killer T (iNKT) cells are a subpopulation of T lymphocytes that bridge the innate and adaptive immune systems (40)

Palmitic, oleic, linoleic or linolenic acid dose-dependently stimulated active GLP-1 secretion from cells (Fig