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Description
Key takeaways : With 65% of patients dropping off therapy, the winners will build adherence, retention, and support ecosystems

After the success of peptide agonists of GLP-1R (a class B G-protein coupled receptor) in the treatment of diabetes, drug discovery scientists saw the opportunity for small molecule agonists of GLP-1R

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By promoting nitric oxide production, these peptides facilitate vasodilation and help regulate healthy blood flow throughout the cardiovascular system

The concentration of tirzepatide per milliliter remains the key number for dosing calculations
Next, we assessed glycolytic flux by measuring extracellular acidification rates (ECAR) using the XF e 96 flux analyzer