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Total weight loss by week 12 typically ranges from 5% to 8% of starting body weight, depending on the medication and dose

Fourth, the absence of corroborating human genetic or observational evidence weakens the case for continued development, particularly when coupled with marginal preclinical effects

Your weight loss journey should be healthy, not painful
The weight regain risk, even for just 4-8 weeks, feels too high

he draws a parallel with depression, which was long viewed as a personal weakness, but is now recognized as a medical condition that cant be self-treated

& Kanasaki, K
