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Gallbladder and biliary disease: GLP-1based therapies have been associated with an increased risk of gallbladder problems, including gallstones and cholecystitis

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The retatrutide dosing schedule escalation was designed to minimize gastrointestinal tolerability issues the primary concern with incretin-based compounds

Anxiogenic-like action of centrally administered glucagon-like peptide-1 in a punished drinking test

Levels of Gcg , Pyy , Pcsk1/3 , and Pax6 mRNAs in the gastric mucosa and intestine did not significantly change after 4 months of high-fat diet (HFD) in rats (Supplementary Fig
