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A 2023 study published in Molecular Psychiatry found that GLP-1 receptor knockout mice displayed hyperactivity, impulsivity, and reduced sustained attention

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In a post hoc analysis of the SUMMIT trial, the decrease in estimated blood volume seen in participants treated with tirzepatide was significantly correlated with decreased blood pressure, lower microalbuminuria, improved KCCQ-CSS, and greater 6-min walking distance [85]