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The most significant results build gradually over the full titration schedule, with clinical trials running over 72 weeks showing an average loss of 22.5% body weight at the highest dose

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Individual Variability in Dose Response: Why 5 mg Isn't Universal Two patients at the same 5 mg dose may experience markedly different responses due to differences in metabolism, gastrointestinal physiology, baseline metabolic rate, and medication interactions

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