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The decision to maintain or increase the dose should be based on individual treatment goals, clinical response, and tolerance to adverse effects

It should not replace these foundations or be framed as a medication alternative

[DOI] [PubMed] [Google Scholar] 32.Van Dijk G, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.EMPA-KIDNEY Collaborative Group Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPAKIDNEY trial