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CRD42022382594 Graphical Abstract Similar content being viewed by others Introduction Semaglutide, administered s.c., has shown superior efficacy compared with other glucose-lowering agents, including its oral formulation, in reducing HbA 1c and in facilitating weight loss in individuals with type 2 diabetes [1, 2]

Accessed January 21, 2026.

However, if someone else is helping you with the injection, the upper arm can be a more comfortable spot for them to administer the medication

Your prescription is shipped directly to your door with free expedited delivery, typically within 12 business days

Use distraction techniques

The drug is the latest entrant into the field of the powerful and pricy class of medications called GLP-1 agonists, which includes Lillys Mounjaro as well as Novo Nordisks Ozempic and Wegovy